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By Hilliard F. Seigler (auth.), H. F. Seigler (eds.)

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Consequently, unless they are aware of the prior pigmented lesion, pathologists are likely to mistake the lesion for an atypical fibroxanthoma on the one hand or a spindle squamous cell carcinoma or soft tissue sarcoma on the other. Thus the key to both the definition and recognition of DM is the prior or concurrent pigmented lesion. To establish the diagnosis one must confirm that a junctional melanoma either precedes or coexists with the lesion or demonstrate melanin production by the tumor cells with special stains or electron microscopy.

Bearman RM, Noe J and Kempson RL: Clear cell sarcoma with melanin pigment. Cancer 36:977-984, 1975. 46. Toe TK and Saw D: Clear cell sarcoma with melanin: a report of two cases. Cancer 41 :235238, 1978. 47. Boudreaux D and Waisman J: Clear cell sarcoma with melanogenesis. Cancer 41: 13871394, 1978. 48. Tsuneyoshi M, Enjoji M and Kubo T: Clear cell sarcoma of tendons and aponeuroses: a comparative study of 13 cases with a provisional subgrouping into the melanotic and synovial types. Cancer 42: 243-252, 1978.

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