By David J. Wilber M.D., Douglas L. Packer M.D., William G. Stevenson M.D.
Radiofrequency Catheter Ablation of Cardiac Arrhythmias has been so greatly up-to-date for its 3rd variation that the booklet now includes a new name: Catheter Ablation of Cardiac Arrhythmias: uncomplicated thoughts and medical functions. The editors convey you 21 polished chapters, every one updating the basics and progressing to complex suggestions, supplying state of the art wisdom with hugely appropriate fabric for knowledgeable electrophysiologists in addition to fellows in training.This streamlined re-creation features:• new editors, either largely released and leaders within the box of catheter ablation• 21 rather than 39 chapters, accomplished by way of targeting basic issues of wide curiosity and assimilating info from a variety of assets• Fewer authors, selected for his or her well-known contributions to the subjects below dialogue, offering a extra built-in and coherent strategy• Anatomic insights from top pathologist Siew Yen Ho, built-in with new details from imaging technologiesEach bankruptcy facing ablation of a particular arrhythmia gains the author's own method of ablation of the arrhythmia, together with functional "how-to" guidance, and a evaluate of power pitfalls. exchange methods and diversifications are succinctly summarized. unique figures and drawings illustrate particular techniques to enhance the usability of the ebook.
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Catheter ablation is largely permitted as an efficient and secure kind of remedy for cardiac arrhythmia. sometimes this healing method is taken into account because the first line of remedy if now not the final word remedy of selection. With using radiofrequency (RF) modality; which has revolutionized the expertise from a barotraumatic, very likely injurious approach utilizing excessive voltage, direct-current (DC) surprise to a secure and comparatively painless one; catheter ablation strategy now contains a truly low danger and is very powerful for particular types of arrhythmia.
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Additional resources for Catheter Ablation of Cardiac Arrhythmias: Basic Concepts and Clinical Applications, Third Edition
Cytoskeleton Mammalian cells are composed of a cytoskeletal filamentous network consisting of three types of filaments: microfilaments, microtubules, and intermediate filaments. In cultured cells, microfilaments, which are primarily composed of actin, form cytoplasmic bundles known as stress filaments. Stress filaments have also been shown to contain myosin, α-actinin, and tropomyosin in addition to actin. Stress filaments provide structural support to the plasma membrane and are responsible for maintaining cellular shape and morphology.
26 Atiga WL, Worley SJ, Hummel J, et al. Prospective randomized comparison of cooled radiofrequency versus standard radiofrequency energy for ablation of typical atrial flutter. Pacing Clin Electrophysiol 2002;25:1172–8. 27 Haines DE. Determinants of lesion size during radiofrequency catheter ablation: the role of electrode–tissue contact pressure and duration of energy delivery. J Cardiovasc Electrophysiol 1991;2:509–15. 28 Whayne JG, Nath S, Haines DE. Microwave catheter ablation of myocardium in vitro: assessment of the characteristics of tissue heating and injury.
In cultured mammalian cells, hyperthermia causes blebbing of the plasma membrane, which has been correlated with the loss of cellular viability . Blebbing of the plasma membrane also occurs after exposure of cultured cells to trypsin, local anesthetics, actinomycin D, and cytochalasin . These agents are known to affect the cellular cytoskeleton. Thus, heat-induced blebbing of the plasma membrane and cell death observed in cultured cells may be caused by disruption of the cytoskeletal network.