Download Breast Cancer: Biological and Clinical Progress: Proceedings by Demetrios A. Spandidos (auth.), L. Dogliotti, A. Sapino, G. PDF

By Demetrios A. Spandidos (auth.), L. Dogliotti, A. Sapino, G. Bussolati (eds.)

The struggle opposed to breast melanoma is anticipated to be successfully influenced by means of interdisciplinary techniques and cross-fertilization among laboratory and medical examine findings. Of significant significance are accordingly conferences selling quick move to scientific purposes of findings through simple scientists. the current quantity, reporting the complaints of the 1991 Biennial convention of the overseas organization for Breast melanoma study, hopes to accomplish this objective via providing the newest observations within the laboratory and their attainable functions for diagnostic reviews and scientific remedies. The sections of the booklet concentration first at the oncogenes much more likely all for mammary tumorigenesis and at the polypeptide elements and steroid hormones affecting proliferation and probably inducing carcinogenesis in breast epithelium. a piece is dedicated to the epidemiological experiences and to the id of possibility components, how to pick out populations at larger possibility and, in all likelihood, to assist in combating the affliction. exact emphasis is given to the institution of diagnostic standards and to the choice of prognostic components, which needs to help an efficient healing making plans. it really is our wish that this quantity, a well timed replace of the newest advances in particular fields offered by way of uncomplicated scientists, pathologists and clinicians will stimulate new insights and progresses top eventually to the keep an eye on of breast cancer.

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Extra resources for Breast Cancer: Biological and Clinical Progress: Proceedings of the Conference of the International Association for Breast Cancer Research, St. Vincent, Aosta Valley, Italy, May 26–29, 1991

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In the whole series of samples, a 9kb transcript was detected. 2kb MET transcripts were also found. Surgical specimens were also analyzed by Western blotting. The results are summarized in 16 Table 2. The Met protein was expressed in all the tumors of the gastrointestinal tract examined. In a third of the cases of carcinomas of the stomach and colon, it was possible to compare the normal and neoplastic tissues of the same patient; in the whole series, the amount of p19ifET was found to be increased in the neoplastic tissue.

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